We are looking for a talented Senior MES Engineer (Pharma) to support and enhance Manufacturing Execution Systems used in regulated pharmaceutical manufacturing environments.

We are a global life sciences manufacturing organization focused on modernizing and expanding paperless manufacturing operations through enterprise MES platforms.

Role Basics

• Work Location: Hybrid onsite in Durham, NC (4 days per week)

• Employment Type: Contract-to-Hire

• Rate Range: $60–$70/hr W2

This role is NOT eligible for visa sponsorship or C2C

Job Duties:

• Support and maintain PMX or Plex or FactoryTalk PharmaSuite MES systems in GMP manufacturing operations

• Troubleshoot MES issues and act as a Tier 2 escalation point for production support

• Assist with MES deployments, upgrades, and functional enhancements across manufacturing sites

• Develop, configure, and support Electronic Batch Records (EBRs) and Master Batch Records (MBRs)

• Partner with engineering, manufacturing, IT, and quality teams to deliver compliant MES solutions

• Maintain validation documentation throughout the system lifecycle (CSV)

• Contribute to MES standardization and site‑to‑site replication initiatives

Ideal Background:

• 5+ years of experience supporting Manufacturing Execution Systems (MES) within pharmaceutical manufacturing industry.

• Experience with Recipe Authoring for PFS (prefilled syringe) or similar Parenteral pharmaceuticals

• Hands-on experience with PMX or Plex or FactoryTalk PharmaSuite in a pharmaceutical manufacturing environment (or other MES platforms such as: Siemens Opcenter, SAP Digital Manufacturing, NoMuda VisualFactory, Infor MES, Tulip Platform, iBase-t Solumina MES, Oracle Cloud Manufacturing, Dassault Systems DELMIA Apriso, DELMIAWORKS, HYDRA X, GE Vernova Proficy Smart Factory, L2L (Leading2Lean), Werum PAS-X MES Suite by Korber Pharma, iTAC.MOM.Suite by iTAC Software, ProManage, TrakSYS by Parsec, 42Q, AVEVA Manufacturing Execution System, Trackwise by Honeywell, Honeywell Forge Operations Management, PINpoint MES, Emerson Syncade,MasterControl Manufacturing Excellence, Aegis Software FactoryLogix, Epicor Advanced MES, Sepasoft MES, ABB Ability Manufacturing Operations Management Suite, Tempo Manufacturing Cloud, Aptean Process Manufacturing OEE, Accevo MES, DeltaV Manufacturing Execution System by Emerson, AspenONE MES, Nexplant MESplus, Cantier MES, or Vimachem Pharma MES)

• Familiarity with GAMP 5, 21 CFR Part 11, and Annex 11

• Working knowledge of GMP, CSV, and regulated systems

• Bachelor’s degree in Engineering, Computer Science, IT, or equivalent experience

Why Us:

• Contract‑to‑hire opportunity with long‑term career potential

• Hands‑on role supporting critical pharmaceutical manufacturing systems

• Exposure to enterprise MES modernization and PharmaSuite transformation initiatives

• Collaborative, cross‑functional environment with engineering, IT, and quality teams

• Competitive hourly rate and on‑call rotation compensation

If this is a role that interests you and you’d like to learn more, click apply now and a recruiter will be in touch with you to discuss this great opportunity. We look forward to speaking with you!

About ManpowerGroup, Parent Company of: Manpower, Experis, Talent Solutions, and Jefferson Wells

ManpowerGroup® (NYSE: MAN), the leading global workforce solutions company, helps organizations transform in a fast-changing world of work by sourcing, assessing, developing, and managing the talent that enables them to win. We develop innovative solutions for hundreds of thousands of organizations every year, providing them with skilled talent while finding meaningful, sustainable employment for millions of people across a wide range of industries and skills. Our expert family of brands – Manpower, Experis, Talent Solutions, and Jefferson Wells – creates substantial value for candidates and clients across more than 75 countries and territories and has done so for over 70 years. We are recognized consistently for our diversity - as a best place to work for Women, Inclusion, Equality and Disability and in 2022 ManpowerGroup was named one of the World's Most Ethical Companies for the 13th year - all confirming our position as the brand of choice for in-demand talent.

ManpowerGroup is committed to providing equal employment opportunities in a professional, high quality work environment. It is the policy of ManpowerGroup and all of its subsidiaries to recruit, train, promote, transfer, pay and take all employment actions without regard to an employee's race, color, national origin, ancestry, sex, sexual orientation, gender identity, genetic information, religion, age, disability, protected veteran status, or any other basis protected by applicable law.